OxyContin 80 mg (Oxycodone Hydrochloride Extended-Release)
Key Information
- Generic Name: Oxycodone Hydrochloride
- Brand Name: OxyContin 80 mg
- Strength: 80 mg
- Dosage Form: Extended-Release Oral Tablet
- Drug Class: Opioid Analgesic (Schedule II Controlled Substance)
- Indication: Management of severe, around-the-clock pain requiring long-term opioid treatment when alternative options are inadequate
- Prescription Status: Strictly Prescription Only (U.S. Federal Law Prohibits Dispensing Without a Valid Prescription)
Product Overview
OxyContin 80 mg is a high-strength extended-release formulation of oxycodone designed for patients who require continuous, long-term pain management. It is typically prescribed for individuals with severe chronic pain who have developed tolerance to lower-dose opioid therapies.
How It Works
Oxycodone acts on mu-opioid receptors in the central nervous system to alter pain perception and emotional response to pain. The extended-release formulation delivers medication gradually over a 12-hour period, providing sustained analgesia.
Indications & Uses
- Chronic severe pain requiring continuous opioid treatment
- Cancer-related pain
- Pain unresponsive to non-opioid or immediate-release medications
Dosage & Administration
- Administer exactly as prescribed by a licensed healthcare provider
- Typically taken every 12 hours
- Swallow tablets whole; do not crush, chew, or dissolve
- Dosage must be individualized based on patient tolerance and prior opioid use
Important Safety Information
Boxed Warning
OxyContin carries a boxed warning for addiction, abuse, misuse, life-threatening respiratory depression, accidental ingestion, and neonatal opioid withdrawal syndrome.
Warnings and Precautions
- High risk of addiction, misuse, and overdose
- May cause severe respiratory depression, especially in opioid-naïve patients
- Avoid use with alcohol or other central nervous system depressants
- Use caution in patients with respiratory disorders, liver impairment, or head injury
Common Side Effects
- Constipation
- Nausea and vomiting
- Drowsiness or sedation
- Dizziness
Serious Risks
- Respiratory depression
- Dependence and withdrawal symptoms
- Overdose (may be fatal)
Who Should Not Use This Medication
- Patients with significant respiratory depression
- Individuals with acute or severe bronchial asthma in unmonitored settings
- Patients with known or suspected gastrointestinal obstruction
Storage Guidelines
- Store at controlled room temperature (20°C to 25°C / 68°F to 77°F)
- Keep securely stored to prevent misuse or theft
- Dispose of unused medication through authorized take-back programs
Regulatory & Compliance Notice
This medication is a Schedule II controlled substance regulated by the DEA. Dispensing requires a valid prescription from a licensed U.S. healthcare provider. Misuse may result in severe legal and health consequences.
FAQ
Is OxyContin 80 mg suitable for new patients?
No. This strength is typically reserved for opioid-tolerant patients under strict medical supervision.
Can the tablet be split or crushed?
No. Altering the tablet can result in rapid release of a potentially fatal dose.
How long does it last?
Each dose is designed to provide pain relief for approximately 12 hours.
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